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While this review summarizes the current evidence from preclinical and clinical studies, most of the existing findings are based on animal models or short-term use human studies, which may not fully reflect the consequences of regular use in humans

Chest pain can come from the heart as well as the lungs

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But, he said, our review of the evidence found e-cigarette use carries a fraction of the risk of smoking, a conclusion reiterated by the Royal College of Physicians earlier this year