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Finally, we conducted sensitivity analyses to assess whether our results changed when using an alternative age covariate (fewer categories, quantitative, or restricted cubic spline) or when only considering adults (ages 20 years)

Fatigue : A sense of tiredness or lethargy, related to the bodys declined energy levels after nicotine, which normally increases alertness and energy

For example, the messenger epinephrine is released into the bloodstream, leading to temporary narrowing of blood vessels, higher blood pressure, and increased heart rate

This includes nausea, stomach pain, and diarrhea due to the irritating effects of concentrated nicotine on your digestive tract lining

Forty-nine states plus D.C