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Clinical Trials Evaluating the Impact of Incretins on MASH and Liver Fibrosis Resolution Many clinical trials have been conducted in recent years to evaluate the effects of incretins on MASLD, and these have been summarized in several reviews [71, 74,75,76,77,78]

While the IGF-1 and KGF pathways have been reproducibly demonstrated across multiple murine models, direct human validation of these intermediates in IBD tissue remains limited, representing a key translational gap