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Under physiological conditions, renal tubular epithelial cells highly express the carnitine transporter OCTN2 (SLC22A5), which mediates active reabsorption of filtered carnitine with an efficiency exceeding 95%

Electrolytes, B vitamins, magnesium, and fiber support are still valuable given the GI effects

To stop this cycle, the hair loss and the itching must be addressed simultaneously

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Consistent with the upregulation of ZnT8 observed in human diabetic cells, ZnT8 expression was significantly increased in cells from HFD-fed mice compared with those from ND-fed controls (Supplementary information, Fig