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By Administration Route Most GLP-1 receptor agonists are administered by subcutaneous injection because they are peptide-based molecules that would be degraded by digestive enzymes if taken orally

This week, seven of those compounds go before the FDA's Pharmacy Compounding Advisory Committee at the White Oak Campus, where AAPM is presenting the case for their inclusion on the 503A Bulk Drug Substances List

It has also been suggested that an increased luminal bile salt concentration would have an osmotic effect, which could lead to the diarrhoea associated with metformin treatment [72]