Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons
Lacking in vitamin B12 can cause tiredness, muscle weakness, problems with memory and mood changes
Clinical trial of the effects of vitamin D supplementation on psychological symptoms and metabolic profiles in maintenance methadone treatment patients
Vitamin B12 and Human Health Vitamin B12, also called cobalamin, is a micronutrient found in animal flesh and animal byproducts like eggs and dairy
However, some patients receiving high-dose B12 supplementation or injections may experience adverse reactions, though these relate to the treatment rather than the elevated levels: Possible reactions to B12 supplementation (particularly injections): Skin reactions, including acneiform eruptions or rashes Pruritus (itching) Injection site reactions (with parenteral administration) Rare hypersensitivity reactions Non-specific symptoms such as headaches, dizziness, or gastrointestinal disturbances have been reported by some patients taking B12 supplements, but causality is not well established in clinical evidence
