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In nematodes, transient diet scarcity blunts reproduction by inducing latency in germline stem cells, a reversible process which is undone once ambient nutritional factors improve [47, 48]

If youre high-risk (active GI symptoms, recent dose increase, known delayed emptying), your team may use a liquid diet the day prior, point-of-care gastric ultrasound, or a brief medication hold

Exclusion criteria We excluded non-human studies, participants aged 12 months or variable), as well as random-effects meta-regression using follow-up duration (in months) as a continuous moderator

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The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal heart attack, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90)