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Neuronglia communication shapes synaptic activity, energy metabolism, immune responses, and circuit plasticity

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The IC50 values of conventional quercetin and resveratrol and NLC gel of quercetin and resveratrol were observed to be 86.50 M and 123.64 M, respectively [298]

Although these models have yielded invaluable insights into core pathways like pyroptosis and ferroptosis, they fail to fully recapitulate human pathophysiology due to species-specific differences in thermoregulation, inflammatory response kinetics, and hepatocyte metabolism