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Product Specifications Form: Lyophilized powder Amount: 10mg total (5mg CJC-1295 No DAC + 5mg Ipamorelin) Purity: 98% Appearance: White to off-white powder Molecular Information CJC-1295 No DAC Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Gly-Ser Ipamorelin Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH CAS (CJC-1295 No DAC): 863288-34-0 CAS (Ipamorelin): 170851-70-4 Research Applications Peptide-receptor interaction research Cellular signaling pathway investigations Neuroendocrine pathway research models Multi-peptide interaction studies in controlled laboratory environments Storage Store lyophilized material in a cool, dry environment
Tesamorelin Recommended for body recomposition Pros Has been shown to selectively reduce abdominal fat in patients with HIV Can also increase muscle area and strength Promising implications for cognitive and cardiovascular health No reported risk of immunogenicity Cons Studies so far have focused on patients with HIV May cause flu-like symptoms Usually administered by subcutaneous injection Prohibited by the World Anti-Doping Agency Tesamorelin is FDA-approved specifically for HIV-associated lipodystrophy excess abdominal lipid accumulation as a result of antiretroviral therapy its efficacy against which was evidenced in a 2010 clinical trial that demonstrated an 18% decrease in visceral fat in intervention subjects compared to placebo.11 Concerning muscle growth, a later study of HIV patients determined that tesamorelin was effective in increasing skeletal muscle area and density.28 Also, because visceral fat is associated with increased cardiovascular mortality, tesamorelin exhibits promise as a treatment for serious health conditions like heart disease and stroke.37 Although tesamorelin studies so far have understandably centered on patients with HIV, theory holds that the peptide should have the same effects on other users
That said, the following titration table reflects the prevailing clinical approach used by longevity-focused practitioners, calibrated against the available pharmacological data
More recent work has examined boron-rich derivatives (PMID 30168238) and PET-imaging-relevant peptidomimetic derivatives (PMID 30282322), broadening the SAR landscape around the original compound
