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AlphaFold calculations were carried out on a computer cluster established with support from the Department of Molecular Biology and Genetics, Aarhus University, and the Danish Research Agency through the Danish national research infrastructure for cryo-electron microscopy (EMBION 5072-00025B)

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Research has mainly focused on short-chain fatty acids, tryptophan metabolites, and ghrelin as well as the impact of probiotic, prebiotic and symbiotic supplementation on their production

Acknowledgements This research was partially supported by NSF grants DMS-0616710(MR, HFN) and EF-1038593(HFN, MR) and NIH grant R01 ES019876 (D