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The first one to three months: Published clinical data suggests this is the window when many patients begin to see results meaningful enough to measure

D'AGOSTINO AN, SOULE EH, MILLER RH: Primary malignant neoplasms of nerves (malignant neurilemomas) in patients without manifestations of multiple neurofibromatosis (von Recklinghausen's disease)

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And when PEA was added to the DLX + PGB combination, there was further significant improvement in pain symptoms compared to DLX + PGB alone [60]