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*In this article, as in most public health messages, tobacco use refers to the use of commercial tobacco products like cigarettes and chewing tobacco as opposed to traditional uses of tobacco .

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Maternal smoking during pregnancy has been shown to alter umbilical cord blood DNA methylation in various genes such as aryl-hydrocarbon receptor repressor ( AHRR ), cytochrome P450 family 1 subfamily A member 1 ( CYP1A1 ), growth factor-independent 1 transcriptional repressor ( GFI1 ), and myosin IG ( MYO1G ) 30,31

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