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Protein helps maintain muscle mass while taking GLP-1 medications

One 2022 review of studies in Frontiers in Nutrition on berberine supplementation for adults with cardiovascular disease risk found that supplementing it reduced weight and body mass index (BMI), as well as other metrics like cholesterol and blood pressure

Clinical trials have shown that a daily 25mg Wegovy pill can result in an average 16.6% body weight reduction after 64 weeks compared to 2.7% with a placebo

Others take longer, and if B12 wasnt the cause, you may notice little change

BV-2 cells were treated for 15 min with various concentrations of BCTC (0.02, 0.5, 2 mmol/L), then incubated with different concentrations (2, 20, 50 mmol/L) of AM404 for a further 15 min period, before being stimulated with LPS