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In patients with micrognathia (small jaw) or retrognathia, the chin is posteriorly displaced causing the tongue to fall backward toward the posterior pharyngeal wall

Hydration is important for the enzymes responsible for desquamation, which helps dead cells shed properly

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It eventually induces ferroptosis in many cell lines and maybe in chondrocytes as well [80]

The cells were then washed once in ice-cold PBS, trypsinized, pelleted, and then homogenized in mitochondrial isolation buffer (0.21 M mannitol, 0.07 M sucrose, 0.1 mM EDTA, 1 mM EGTA, 10 mM Tris HCl, 0.5% BSA, pH 7.4 using KOH)