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Simon DI, Stamler JS, Jaraki O, Keaney JF, Osborne JA, Francis SA, Singel DJ, and Loscalzo J (1993)

The effect of ROS in mitochondria is through disruption in the electron transport chain and activation of inflammatory cells 15

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DMF mediates NRF2-dependent and independent mechanisms on TSS pathway CBS activation DMF activates NRF2, the master regulator for the antioxidative stress response, to regulate the expression of proteins involved in iron hemostasis, and GSH synthesis such as HMOX1, NQO1, FTH, FTL, SLC40A1 in a variety of cellular systems 37

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