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I have seen patients push their dose without oversight and end up with significant side effects and no better results

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Parkinsons disease Clinical exploration into the application of GLP-1 medicines in PD began in 2013 with an open-label pilot study (NCT01174810), which tested exenatide 10 g twice daily in 45 patients with moderate PD over a 1-year period

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To achieve the best results, it must be combined with diet and lifestyle changes, such as regular physical activity, and ongoing support from medical experts