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Trials showed the most effective use was injection near the injury site to target local healing

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5.4 Pharmacological effects of SIN in other diseases SIN has exhibited therapeutic efficacy in various diseases, including colitis (119), atherosclerosis (120), myocardial ischemiareperfusion injury (100), chronic sciatic nerve injury (CCI) (121), renal injury (122), colorectal cancer (123), lung cancer, liver cancer, cervical cancer, bladder cancer, gastric cancer, and renal cancer (93, 124, 125)