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While loss of p53 function may weaken the apoptotic signaling response mediated by DNA damage related to chemotherapy resistance [127], thinking about strategies to reduce side effects without compromising p53 function will be of widespread value in cancer treatment

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In vitro and animal models have been used to detect the potential toxicity of NPs, which demonstrate neurotoxic effects of NPs, e.g., neuroinflammation and neurodegeneration in the CNS

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The company develops glutathione affinity chromatography products supporting recombinant protein purification and vaccine research programs