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In a BPC-157 study, (11) three experimental murine models were used as subjects where all were experimentally wounded, with either acute or chronic wounds

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2.5.2 The Keap1-NRF2 pathway mediates ferroptosis The NRF2 transcription factor stimulates the production of NADPH by blocking the expression of antioxidant genes and increasing the expression of enzymes in the pentose phosphate pathway, which decreases the sensitivity of cells to ferroptosis (85)