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This is good news as it makes the chance of severe nicotine toxicosis less likely

These changes contribute to the development of addiction and make quitting tobacco use challenging for many individuals

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doi:10.1111/j.1600-0714.2007.00582.x 12

Smokers with hypertension showed reduced enrichment of beneficial taxa such as Phycisphaera and Clostridium asparagiforme , alongside altered microbial functions, highlighting the detrimental impact of smoking on gut health and its potential role in cardiovascular risk [117]