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Additionally, ethanol-induced OS is one of the factors involved in the activation of the mammalian target of rapamycin (mTOR), which is essential to premature senescence in cementoblasts and human periodontal ligament cells (Figure 2)

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Gene structure and expression of the glutathione Stransferase, SiGSTS1, from the red imported fire ant, Solenopsis invicta

But here's the detail you should know: not having enough glutathione contributes to oxidative stress, which plays a major role in the mechanisms of complex disorders

Mathew, R