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Strand breaks can be measured by the alkaline unwinding procedure, based on the discovery that double-stranded DNA (dsDNA) unwind in an alkaline solution from free ends

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It then binds to intrinsic factor (IF), a glycoprotein secreted by the parietal cells of the gastric mucosa

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HUBERMAN: And in addition to wanting to teach you about some of the biology of these peptides and how they work and what they're designed to do, as well as some of their potential therapeutic benefits under the right conditions, again, working with a really good board-certified physician and making sure that the sourcing is really clean