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The authors also emphasized that the wider use of these drugs should consider social and commercial determinants of health, including access, affordability and insurance coverage, to avoid deepening existing health inequities among people living with obesity

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arginine 3) works by binding to IGF-1 receptors located on muscle satellite cells, initiating signalling pathways that drive protein synthesis while inhibiting protein breakdown

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