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In PCOS, the convergence of hyperandrogenismdriven adipokine dysregulation, insulin resistance, and macrophage infiltration arguably sets up a permissive environment for neutrophil activation: elevated adipokines such as leptin, resistin, and visfatin have been documented in PCOS and linked to chronic inflammatory signaling in adipose and reproductive tissues [90]

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Nutrients that Stimulate GLP-1 Secretion (also known as secretagogues) GLP-1 is produced in L cells which are abundant in the lining of the large intestine (Figure 3)