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Inhibition of NNMT has been explored in preclinical research for potential effects on adiposity regulation, insulin sensitivity, and metabolic efficiency

Those with milder deficiencies or who prefer oral supplements may find pills sufficient, provided they monitor their B12 levels regularly

Determining the correct B12 dosage can be tricky, as the appropriate amount depends on factors such as age, the severity of deficiency, and any coexisting conditions

Thus, research interest has focused on the development of early detection techniques via monitoring saliva, serum, CSF, neuroimaging biomarkers, and cognitive dysfunction [31]