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REASONS FOR COLONOSCOPY The most common reasons for colonoscopy are: To screen for colon polyps (growths of tissue in the colon) or colon cancer Rectal bleeding A change in bowel habits, like persistent diarrhea Iron deficiency anemia (a decrease in blood count due to loss of iron)A family history of colon cancer A personal history of colon polyps or colon cancer Chronic, unexplained abdominal or rectal pain An abnormal x-ray exam, like a barium enema or CT scan GETTING READY FOR COLONOSCOPY Preparation: Before colonoscopy, your colon must be completely cleaned out so that the doctor can see any abnormal areas