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Submitted by Harley Robinson, DVM

The problem is, those metabolites are constantly being secreted from your bloodstream back into your saliva

FDA over-regulation

The convergence of acetaldehyde-producing fungi, oncoviral cofactors (HPV/EBV), and nitrosamine-enriched bacterial consortia establishes a polymicrobial carcinogenic milieu, necessitating functional metagenomic studies to disentangle microbial contributions to OSCC progression and targeted interventions to restore mucosal homeostasis

For instance, male heavy smokers have been found to have a 20% to 40% reduction in serum ascorbic acid levels, but when they are given as supplements the sperm quality has been shown to improve [111,112]