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347,348,349 Similarly, MSU promotes the expression of other cytokines, such as interleukin-6 (IL-6), tumor necrosis factor- (TNF-), and interferon gamma (IFN-), and chemokines, such as monocyte chemotactic protein-1 (MCP-1)

doi: 10.1080/08916930600597326 [DOI] [PMC free article] [PubMed] [Google Scholar] 17

They are also potential candidates for peptidomimetics for studying protein-protein, protein-peptide, and peptide-peptide interactions

It directly binds to oxidative compounds that damage cell membranes, DNA and energy production

The beneficial effects of polyphenols on the state of intestinal epithelium are associated with beneficial effects on the state of TJs and an increase in mucus production, as well as effects on the activity of several protein kinases