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In addition, this review highlights the essential role of TAMs, via CCL5 and VCAM-1 pathways, in E-cig induced acceleration of BC tumor development

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This insight is translationally valuable as nicotine-induced alterations in explore/exploit processes likely also have implications for the everyday life of smokers, particularly as they can increase vulnerability for addiction to other drugs of abuse and for behavioral disorders such as pathological gambling that rely on value-based decisions 7,59 and present a high comorbidity with tobacco addiction 60

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